HealthDay Reporter
THURSDAY, Dec. 2, 2021 (HealthDay News) -- Which coronavirus vaccine is champion astatine beating COVID-19 -- Moderna oregon Pfizer?
New probe hands that grant to Moderna: In what is billed arsenic the archetypal head-to-head examination of the 2 shots, researchers analyzed the wellness records of astir 440,000 U.S. veterans who received 1 of the 2 vaccines betwixt aboriginal January 2021 and mid-May 2021. All were followed for 24 weeks.
While some vaccines were highly effectual successful preventing infection, hospitalization and death, the Moderna vaccine conferred a 21% little hazard of corruption and a 41% little hazard of hospitalization.
“Both vaccines are incredibly effective, with lone uncommon breakthrough cases,” said probe squad subordinate Dr. J.P. Casas, an epidemiologist and subordinate prof with Brigham and Women’s Hospital and Harvard Medical School. He is besides enforcement manager of the U.S. Department of Veterans Affairs (VA) Million Veteran Program for genetics and wellness research.
“But careless of the predominant strain -- Alpha earlier and past Delta aboriginal -- Moderna was shown to beryllium somewhat much effective,” Casas noted successful a VA quality release.
The corruption complaint during the follow-up play was 4.52 per 1,000 successful the Moderna vaccine radical and 5.75 per 1,000 successful the Pfizer group. Those successful the Pfizer radical besides had higher rates of symptomatic COVID-19 (0.44 much per 1,000), hospitalization (0.55 much per 1,000), ICU admittance (0.10 much per 1,000), and decease (0.02 much per 1,000) than those successful the Moderna group.
An further signifier of the survey covering the play erstwhile Delta was the main strain successful the United States showed that the hazard of corruption was inactive higher among those successful the Pfizer radical (6.54 much per 1,000) than successful the Moderna group.
The findings were published Dec. 1 successful the New England Journal of Medicine.
“Given the precocious effectiveness of some the Moderna and Pfizer vaccines, confirmed by our study, either 1 is recommended to immoderate idiosyncratic offered a prime betwixt the two,” said survey archetypal writer Barbra Dickerman, an epidemiology teacher astatine the Harvard T.H. Chan School of Public Health.
“However, portion the estimated differences successful effectiveness were tiny connected an implicit scale, they whitethorn beryllium meaningful erstwhile considering the ample colonisation standard astatine which these vaccines are deployed. This accusation whitethorn beryllium adjuvant for larger decision-making bodies,” Dickerman said successful the release.
Further valuation of the 2 vaccines' effectiveness and information is needed, but fixed "the precocious effectiveness and information illustration of some mRNA vaccines, either 1 is powerfully recommended," the researchers concluded.
Previous randomized trials recovered that the Pfizer vaccine was 95% effectual and the Moderna vaccine 94% effectual against symptomatic COVID-19 infection, and akin levels of extortion were recovered successful real-world use.
More information
The U.S. Centers for Disease Control and Prevention has much connected COVID-19 vaccines.
SOURCE: U.S. Department of Veterans Affairs, quality release, Dec. 1, 2021
English (US) ·